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BDBM359445 US10221129, Example CA-132

SMILES: CN(C(=O)[C@H](Cc1cc(F)cc(F)c1)NC(=O)NS(=O)(=O)NC1CCC1)c1ccc2scnc2c1

InChI Key: InChIKey=VICINJFDHIDDAR-IBGZPJMESA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 359445   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Envelope glycoprotein gp160


(Human immunodeficiency virus type 1 (isolate BRU/L...)
BDBM359445
PNG
(US10221129, Example CA-132)
Show SMILES CN(C(=O)[C@H](Cc1cc(F)cc(F)c1)NC(=O)NS(=O)(=O)NC1CCC1)c1ccc2scnc2c1
Show InChI InChI=1S/C22H23F2N5O4S2/c1-29(17-5-6-20-18(11-17)25-12-34-20)21(30)19(9-13-7-14(23)10-15(24)8-13)26-22(31)28-35(32,33)27-16-3-2-4-16/h5-8,10-12,16,19,27H,2-4,9H2,1H3,(H2,26,28,31)/t19-/m0/s1
PDB

UniProtKB/TrEMBL

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 50n/an/an/an/a



ViiV HEALTHCARE UK (NO. 5) LIMITED

US Patent


Assay Description
HIV cell culture assay-MT-2 cells, 293T cells and the proviral DNA clone of NL4-3 virus were obtained from the NIH AIDS Research and Reference Reagen...


US Patent US10221129 (2019)


BindingDB Entry DOI: 10.7270/Q2R213N8
More data for this
Ligand-Target Pair