BDBM3595 4-N-(3-bromophenyl)-7-N,7-N-dimethylpyrido[4,3-d]pyrimidine-4,7-diamine::4-[(3-Bromophenyl)amino]-7-(dimethylamino)pyrido-[4,3-d]pyrimidine::CHEMBL53428::Pyrido[4,3-d]pyrimidine 5g

SMILES CN(C)c1cc2ncnc(Nc3cccc(Br)c3)c2cn1

InChI Key InChIKey=FKFFXIBNVYSRTJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 3595   

TargetEpidermal growth factor receptor(Homo sapiens (Human))
University Of Auckland

LigandPNGBDBM3595(4-N-(3-bromophenyl)-7-N,7-N-dimethylpyrido[4,3-d]p...)
Affinity DataIC50:  0.0900nMpH: 7.4 T: 2°CAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
University Of Auckland

LigandPNGBDBM3595(4-N-(3-bromophenyl)-7-N,7-N-dimethylpyrido[4,3-d]p...)
Affinity DataIC50:  0.0910nMpH: 7.4 T: 2°CAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed