BDBM3603 4-N-(3-bromophenyl)-6-N-methylpyrido[3,4-d]pyrimidine-4,6-diamine::4-[(3-bromophenyl)amino]-6-(methylamino)pyrido[3,4-d]pyrimidine::CHEMBL53753::PD158780

SMILES: CNc1cc2c(Nc3cccc(Br)c3)ncnc2cn1

InChI Key: InChIKey=KFHMLBXBRCITHF-UHFFFAOYSA-N

Data: 5 IC50

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Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 3603   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Epidermal growth factor receptor (Human)	BDBM3603 (4-N-(3-bromophenyl)-6-N-methylpyrido[3,4-d]pyrimid...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.00800	n/a	n/a	n/a	n/a	7.4	22
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Epidermal growth factor receptor (Human)	BDBM3603 (4-N-(3-bromophenyl)-6-N-methylpyrido[3,4-d]pyrimid...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.00800	n/a	n/a	n/a	n/a	7.4	22
TBA									Citation and Details
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Human)	BDBM3603 (4-N-(3-bromophenyl)-6-N-methylpyrido[3,4-d]pyrimid...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.00800	n/a	n/a	n/a	n/a	7.4	22
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Activated CDC42 kinase 1 (Human)	BDBM3603 (4-N-(3-bromophenyl)-6-N-methylpyrido[3,4-d]pyrimid...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
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MAP kinase-interacting serine/threonine-protein kinase 1 (Human)	BDBM3603 (4-N-(3-bromophenyl)-6-N-methylpyrido[3,4-d]pyrimid...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair