BDBM361714 US10221177, Compound 77

SMILES C[C@@H](C(=O)Nc1cncc(n1)-c1ccc(nc1)N1CC2C(C1)C2(F)F)n1cnc2n(C)c(=O)n(CC#N)c(=O)c12

InChI Key InChIKey=NHABUIFDSBXZLP-JEYLPNPQSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 361714   

TargetTransient receptor potential cation channel subfamily A member 1(Homo sapiens (Human))
Hydra Biosciences

US Patent
LigandPNGBDBM361714(US10221177, Compound 77)
Affinity DataIC50:  2nMAssay Description:Compounds of Formula (I) inhibit the TRPA1 channel, as shown by measuring the in vitro inhibition of human TRPA1, provided in data tables shown in Ta...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent