BDBM363212 (2R,3S)-2-((2-((3-cyanobenzyl)oxy)-6-methoxy-4-((2-methyl-[1,1′-biphenyl]-3-yl)methoxy)benzyl)amino)-3-hydroxybutanoic acid::US9850225, Example 1135

SMILES COc1cc(OCc2cccc(c2C)-c2ccccc2)cc(OCc2cccc(c2)C#N)c1CN[C@H]([C@H](C)O)C(O)=O

InChI Key InChIKey=MWGTVYDWJRCRQT-FLASPHMUSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 363212   

TargetProgrammed cell death 1 ligand 1(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM363212((2R,3S)-2-((2-((3-cyanobenzyl)oxy)-6-methoxy-4-((2...)
Affinity DataIC50:  5.30nMAssay Description:The interaction of PD-1 and PD-L1 can be assessed using soluble, purified preparations of the extracellular domains of the two proteins. The PD-1 and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent