BDBM36335 US10639284, Compound 1.001::US11426364, Compound 1.001
SMILES OC[C@H](NCc1cc(Cl)c(OC2CCc3c2cccc3-c2ccccc2)cc1OCc1cncc(c1)C#N)C(O)=O
InChI Key InChIKey=XINKNBMIVAEBNP-UKDJSQQHSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 36335
Affinity DataIC50: <100nMAssay Description:Plates were coated with 1 μg/mL of human PD-L1 (obtained from R&D) in PBS overnight at 4° C. The wells were then blocked with PBS containing 2% BSA...More data for this Ligand-Target Pair
TargetProgrammed cell death 1 ligand/protein 1(Homo sapiens)
Chinese Academy Of Medical Sciences & Peking Union Medical College
Curated by ChEMBL
Chinese Academy Of Medical Sciences & Peking Union Medical College
Curated by ChEMBL
Affinity DataIC50: <100nMAssay Description:Inhibition of PD-1/PDL1 protein-protein interaction (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: <100nMAssay Description:Plates were coated with 1 μg/mL of human PD-L1 (obtained from R&D) in PBS overnight at 4° C. The wells were then blocked with PBS containing 2% ...More data for this Ligand-Target Pair
Affinity DataIC50: <100nMAssay Description:Inhibition of PDL1 (unknown origin)More data for this Ligand-Target Pair