BDBM36354 4-(6-(4-isopropoxyphenyl)pyrazolo[1,5-a]pyrimidin- 3-yl)quinoline::DMH1::US9040694, 1

SMILES: CC(C)Oc1ccc(cc1)-c1cnc2c(cnn2c1)-c1ccnc2ccccc12

InChI Key: InChIKey=JMIFGARJSWXZSH-UHFFFAOYSA-N

Data: 12 IC50  3 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 15 hits for monomerid = 36354   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Receptor protein serine/threonine kinase (Zebrafish)	BDBM36354 (DMH1 | 4-(6-(4-isopropoxyphenyl)pyrazolo[1,5-a]pyr...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	200	n/a	n/a	n/a	n/a
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Receptor protein serine/threonine kinase (Zebrafish)	BDBM36354 (DMH1 | 4-(6-(4-isopropoxyphenyl)pyrazolo[1,5-a]pyr...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a
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Receptor protein serine/threonine kinase (Zebrafish)	BDBM36354 (DMH1 | 4-(6-(4-isopropoxyphenyl)pyrazolo[1,5-a]pyr...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a
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Activin receptor type-1 (Human)	BDBM36354 (DMH1 | 4-(6-(4-isopropoxyphenyl)pyrazolo[1,5-a]pyr...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	108	n/a	n/a	n/a	n/a	n/a	n/a
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Serine/threonine-protein kinase receptor R3 (Mouse)	BDBM36354 (DMH1 | 4-(6-(4-isopropoxyphenyl)pyrazolo[1,5-a]pyr...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	77.9	n/a	n/a	n/a	n/a	n/a	n/a
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Activin receptor type-1 (Mouse)	BDBM36354 (DMH1 | 4-(6-(4-isopropoxyphenyl)pyrazolo[1,5-a]pyr...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	12.6	n/a	n/a	n/a	n/a	n/a	n/a
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Bone morphogenetic protein receptor type-1A (Mouse)	BDBM36354 (DMH1 | 4-(6-(4-isopropoxyphenyl)pyrazolo[1,5-a]pyr...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	241	n/a	n/a	n/a	n/a	n/a	n/a
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Activin receptor type-1B (Mouse)	BDBM36354 (DMH1 | 4-(6-(4-isopropoxyphenyl)pyrazolo[1,5-a]pyr...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
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TGF-beta receptor type-1 (Mouse)	BDBM36354 (DMH1 | 4-(6-(4-isopropoxyphenyl)pyrazolo[1,5-a]pyr...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.97E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Activin receptor type-1 (Human)	BDBM36354 (DMH1 | 4-(6-(4-isopropoxyphenyl)pyrazolo[1,5-a]pyr...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	108	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Activin receptor type-1 (Human)	BDBM36354 (DMH1 | 4-(6-(4-isopropoxyphenyl)pyrazolo[1,5-a]pyr...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
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Bone morphogenetic protein receptor type-1B (Human)	BDBM36354 (DMH1 | 4-(6-(4-isopropoxyphenyl)pyrazolo[1,5-a]pyr...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	48	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Serine/threonine-protein kinase receptor R3 (Human)	BDBM36354 (DMH1 | 4-(6-(4-isopropoxyphenyl)pyrazolo[1,5-a]pyr...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	27	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Activin receptor type-1B (Human)	BDBM36354 (DMH1 | 4-(6-(4-isopropoxyphenyl)pyrazolo[1,5-a]pyr...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	9.62E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Activin receptor type-1 (Human)	BDBM36354 (DMH1 | 4-(6-(4-isopropoxyphenyl)pyrazolo[1,5-a]pyr...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	108	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair