BDBM36362 CID1620213::Pladienolide analog 10

SMILES [H][C@@]12CS[C@H](CCCCC(=O)N(C)CCN(C)C(=O)[C@H](CCCCNC(=O)O[C@H]3\C=C\[C@H](C)[C@H](OC(=O)C[C@H](O)CC[C@@]3(C)O)C(\C)=C\C=C\[C@@H](C)C[C@H]3O[C@@H]3[C@H](C)[C@@H](O)CC)NC(=O)c3ccc(cc3)C3(N=N3)C(F)(F)F)[C@]1([H])NC(=O)N2

InChI Key InChIKey=NTCKGMJCDAGYMI-HXSXBPABSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 36362   

TargetSplicing factor 3B subunit 3(Homo sapiens (Human))
Eisai

LigandPNGBDBM36362(CID1620213 | Pladienolide analog 10)
Affinity DataEC50:  595nMpH: 7.8 T: 2°CAssay Description:Cell proliferation assay using WiDrMore data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed