BDBM36371 5-(1H-indol-3-ylmethyl)-3-methyl-2-thioxo-4-Imidazolidinone, Nec-1::CID2828334::US10501473, Comparative Example 1::US20250129073, Compound Nec-1

SMILES: CN1C(=S)NC(Cc2c[nH]c3ccccc23)C1=O

InChI Key: InChIKey=TXUWMXQFNYDOEZ-UHFFFAOYSA-N

Data: 4 KI  15 IC50  2 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 21 hits for monomerid = 36371   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Aryl hydrocarbon receptor (Human)	BDBM36371 (CID2828334 | 5-(1H-indol-3-ylmethyl)-3-methyl-2-th...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Receptor-interacting serine/threonine-protein kinase 1 (Human)	BDBM36371 (CID2828334 | 5-(1H-indol-3-ylmethyl)-3-methyl-2-th...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	760	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Indoleamine 2,3-dioxygenase 1 (Human)	BDBM36371 (CID2828334 | 5-(1H-indol-3-ylmethyl)-3-methyl-2-th...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.15E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Receptor-interacting serine/threonine-protein kinase 1 (Human)	BDBM36371 (CID2828334 | 5-(1H-indol-3-ylmethyl)-3-methyl-2-th...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	182	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Indoleamine 2,3-dioxygenase 1 (Human)	BDBM36371 (CID2828334 | 5-(1H-indol-3-ylmethyl)-3-methyl-2-th...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	7.69E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Receptor-interacting serine/threonine-protein kinase 3 (Human)	BDBM36371 (CID2828334 | 5-(1H-indol-3-ylmethyl)-3-methyl-2-th...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Receptor-interacting serine/threonine-protein kinase 1 (Human)	BDBM36371 (CID2828334 | 5-(1H-indol-3-ylmethyl)-3-methyl-2-th...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	268	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Receptor-interacting serine/threonine-protein kinase 1 (Human)	BDBM36371 (CID2828334 | 5-(1H-indol-3-ylmethyl)-3-methyl-2-th...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.98E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Indoleamine 2,3-dioxygenase 1 (Human)	BDBM36371 (CID2828334 | 5-(1H-indol-3-ylmethyl)-3-methyl-2-th...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.91E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Receptor-interacting serine/threonine-protein kinase 1 (Human)	BDBM36371 (CID2828334 | 5-(1H-indol-3-ylmethyl)-3-methyl-2-th...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	182	n/a	n/a	7.3	30
TBA									Citation and Details
					More data for this Ligand-Target Pair
Indoleamine 2,3-dioxygenase 1 (Human)	BDBM36371 (CID2828334 | 5-(1H-indol-3-ylmethyl)-3-methyl-2-th...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	7.69E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Receptor-interacting serine/threonine-protein kinase 1 (Human)	BDBM36371 (CID2828334 | 5-(1H-indol-3-ylmethyl)-3-methyl-2-th...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.14E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Indoleamine 2,3-dioxygenase 1 (Human)	BDBM36371 (CID2828334 | 5-(1H-indol-3-ylmethyl)-3-methyl-2-th...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	7.69E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Indoleamine 2,3-dioxygenase 1 (Human)	BDBM36371 (CID2828334 | 5-(1H-indol-3-ylmethyl)-3-methyl-2-th...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	110	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Indoleamine 2,3-dioxygenase 1 (Human)	BDBM36371 (CID2828334 | 5-(1H-indol-3-ylmethyl)-3-methyl-2-th...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Receptor-interacting serine/threonine-protein kinase 1 (Human)	BDBM36371 (CID2828334 | 5-(1H-indol-3-ylmethyl)-3-methyl-2-th...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.14E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Receptor-interacting serine/threonine-protein kinase 1 (Human)	BDBM36371 (CID2828334 | 5-(1H-indol-3-ylmethyl)-3-methyl-2-th...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	95.5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Indoleamine 2,3-dioxygenase 1 (Human)	BDBM36371 (CID2828334 | 5-(1H-indol-3-ylmethyl)-3-methyl-2-th...) Show SMILES Show InChI	GoogleScholar	UniChem		1.14E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Indoleamine 2,3-dioxygenase 1 (Human)	BDBM36371 (CID2828334 | 5-(1H-indol-3-ylmethyl)-3-methyl-2-th...) Show SMILES Show InChI	GoogleScholar	UniChem		1.14E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Indoleamine 2,3-dioxygenase 1 (Human)	BDBM36371 (CID2828334 | 5-(1H-indol-3-ylmethyl)-3-methyl-2-th...) Show SMILES Show InChI	GoogleScholar	UniChem		1.14E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Indoleamine 2,3-dioxygenase 1 (Human)	BDBM36371 (CID2828334 | 5-(1H-indol-3-ylmethyl)-3-methyl-2-th...) Show SMILES Show InChI	GoogleScholar	UniChem		1.20E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair