BDBM36397 (4-Amino-5-fluorospiro[1H-quinazoline-2,4'-piperidine]-1'-yl)-[4-(aminomethyl)phenyl]methanone, 4::CID24894149

SMILES: c1cc2c(c(c1)F)C(=NC3(N2)CCN(CC3)C(=O)c4ccc(cc4)CN)N

InChI Key: InChIKey=SFPCNWQWKOUNRT-UHFFFAOYSA-N

Data: 3 IC50

PDB links: 1 PDB ID matches this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 36397   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Nitric oxide synthase, inducible (Human)	BDBM36397 (CID24894149 | (4-Amino-5-fluorospiro[1H-quinazolin...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	130	n/a	n/a	n/a	n/a	7.0	37
TBA									Citation and Details
					More data for this Ligand-Target Pair
Nitric oxide synthase, endothelial (Human)	BDBM36397 (CID24894149 | (4-Amino-5-fluorospiro[1H-quinazolin...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	7.0	37
TBA									Citation and Details
					More data for this Ligand-Target Pair
Nitric oxide synthase, brain (Human)	BDBM36397 (CID24894149 | (4-Amino-5-fluorospiro[1H-quinazolin...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>7.80E+3	n/a	n/a	n/a	n/a	7.0	37
TBA									Citation and Details
					More data for this Ligand-Target Pair