BDBM36408 1-cyclobutyl-3-(3,4-dimethoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine, PP494::CID24905153

SMILES: COc1ccc(cc1OC)-c1nn(C2CCC2)c2ncnc(N)c12

InChI Key: InChIKey=ITOYZJGFTNTKKR-UHFFFAOYSA-N

Data: 14 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 14 hits for monomerid = 36408   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (Human)	BDBM36408 (CID24905153 | 1-cyclobutyl-3-(3,4-dimethoxyphenyl)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
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Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha/beta isoform (Human)	BDBM36408 (CID24905153 | 1-cyclobutyl-3-(3,4-dimethoxyphenyl)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	130	n/a	n/a	n/a	n/a	n/a	n/a
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Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha/delta isoform (Human)	BDBM36408 (CID24905153 | 1-cyclobutyl-3-(3,4-dimethoxyphenyl)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
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Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha/beta isoform (Human)	BDBM36408 (CID24905153 | 1-cyclobutyl-3-(3,4-dimethoxyphenyl)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	72	n/a	n/a	n/a	n/a	n/a	n/a
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DNA-dependent protein kinase catalytic subunit/Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (Human)	BDBM36408 (CID24905153 | 1-cyclobutyl-3-(3,4-dimethoxyphenyl)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	47	n/a	n/a	n/a	n/a	n/a	n/a
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Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform/Serine/threonine-protein kinase mTOR (Human)	BDBM36408 (CID24905153 | 1-cyclobutyl-3-(3,4-dimethoxyphenyl)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform/Tyrosine-protein kinase ABL1 (Human)	BDBM36408 (CID24905153 | 1-cyclobutyl-3-(3,4-dimethoxyphenyl)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	340	n/a	n/a	n/a	n/a	n/a	n/a
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Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform/Tyrosine-protein kinase HCK (Human)	BDBM36408 (CID24905153 | 1-cyclobutyl-3-(3,4-dimethoxyphenyl)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	130	n/a	n/a	n/a	n/a	n/a	n/a
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Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform/Proto-oncogene tyrosine-protein kinase Src (Human)	BDBM36408 (CID24905153 | 1-cyclobutyl-3-(3,4-dimethoxyphenyl)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	170	n/a	n/a	n/a	n/a	n/a	n/a
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Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform/Proto-oncogene tyrosine-protein kinase Src (Human-Chicken)	BDBM36408 (CID24905153 | 1-cyclobutyl-3-(3,4-dimethoxyphenyl)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform/Vascular endothelial growth factor receptor 2 (Human)	BDBM36408 (CID24905153 | 1-cyclobutyl-3-(3,4-dimethoxyphenyl)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	7.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform/Receptor protein-tyrosine kinase (Human)	BDBM36408 (CID24905153 | 1-cyclobutyl-3-(3,4-dimethoxyphenyl)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Ephrin type-B receptor 4/Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (Human)	BDBM36408 (CID24905153 | 1-cyclobutyl-3-(3,4-dimethoxyphenyl)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform/Platelet-derived growth factor receptor beta [525-1106] (Human)	BDBM36408 (CID24905153 | 1-cyclobutyl-3-(3,4-dimethoxyphenyl)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	170	n/a	n/a	n/a	n/a	n/a	n/a
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