BDBM36409 2-(4-amino-1-isopropyl-1H-pyrazolo[3,4-d]pyrimidin-3-yl)-1H-indol-5-ol, PP242::CID24905147::US10172858, Table 2.1::US9828378, # 1

SMILES: CC(C)n1nc(-c2cc3cc(O)ccc3[nH]2)c2c(N)ncnc12

InChI Key: InChIKey=MFAQYJIYDMLAIM-UHFFFAOYSA-N

Data: 32 IC50  449 Kd

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 495 hits for monomerid = 36409   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase mTOR (Human)	BDBM36409 (CID24905147 | 2-(4-amino-1-isopropyl-1H-pyrazolo[3...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Phosphatidylinositol 3-kinase regulatory subunit alpha (Human)	BDBM36409 (CID24905147 | 2-(4-amino-1-isopropyl-1H-pyrazolo[3...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>500	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Phosphatidylinositol 3-kinase regulatory subunit beta (Human)	BDBM36409 (CID24905147 | 2-(4-amino-1-isopropyl-1H-pyrazolo[3...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>500	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (Human)	BDBM36409 (CID24905147 | 2-(4-amino-1-isopropyl-1H-pyrazolo[3...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	<500	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Human)	BDBM36409 (CID24905147 | 2-(4-amino-1-isopropyl-1H-pyrazolo[3...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	<500	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cytosolic arginine sensor for mTORC1 subunit 1 (Human)	BDBM36409 (CID24905147 | 2-(4-amino-1-isopropyl-1H-pyrazolo[3...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (Human)	BDBM36409 (CID24905147 | 2-(4-amino-1-isopropyl-1H-pyrazolo[3...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>500	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta (Human)	BDBM36409 (CID24905147 | 2-(4-amino-1-isopropyl-1H-pyrazolo[3...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>500	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (Human)	BDBM36409 (CID24905147 | 2-(4-amino-1-isopropyl-1H-pyrazolo[3...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	<500	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Human)	BDBM36409 (CID24905147 | 2-(4-amino-1-isopropyl-1H-pyrazolo[3...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	<500	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform/Serine/threonine-protein kinase mTOR (Human)	BDBM36409 (CID24905147 | 2-(4-amino-1-isopropyl-1H-pyrazolo[3...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform/Serine/threonine-protein kinase mTOR (Human)	BDBM36409 (CID24905147 | 2-(4-amino-1-isopropyl-1H-pyrazolo[3...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform/Serine/threonine-protein kinase mTOR (Human)	BDBM36409 (CID24905147 | 2-(4-amino-1-isopropyl-1H-pyrazolo[3...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform/Serine/threonine-protein kinase mTOR (Human)	BDBM36409 (CID24905147 | 2-(4-amino-1-isopropyl-1H-pyrazolo[3...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
DNA-dependent protein kinase catalytic subunit/Serine/threonine-protein kinase mTOR (Human)	BDBM36409 (CID24905147 | 2-(4-amino-1-isopropyl-1H-pyrazolo[3...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	410	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase mTOR (Human)	BDBM36409 (CID24905147 | 2-(4-amino-1-isopropyl-1H-pyrazolo[3...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase mTOR/Tyrosine-protein kinase ABL1 (Human)	BDBM36409 (CID24905147 | 2-(4-amino-1-isopropyl-1H-pyrazolo[3...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase mTOR/Tyrosine-protein kinase HCK (Human)	BDBM36409 (CID24905147 | 2-(4-amino-1-isopropyl-1H-pyrazolo[3...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src/Serine/threonine-protein kinase mTOR (Human)	BDBM36409 (CID24905147 | 2-(4-amino-1-isopropyl-1H-pyrazolo[3...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src/Serine/threonine-protein kinase mTOR (Human-Chicken)	BDBM36409 (CID24905147 | 2-(4-amino-1-isopropyl-1H-pyrazolo[3...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase mTOR/Vascular endothelial growth factor receptor 2 (Human)	BDBM36409 (CID24905147 | 2-(4-amino-1-isopropyl-1H-pyrazolo[3...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Receptor protein-tyrosine kinase/Serine/threonine-protein kinase mTOR (Human)	BDBM36409 (CID24905147 | 2-(4-amino-1-isopropyl-1H-pyrazolo[3...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Ephrin type-B receptor 4/Serine/threonine-protein kinase mTOR (Human)	BDBM36409 (CID24905147 | 2-(4-amino-1-isopropyl-1H-pyrazolo[3...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta [525-1106] /Serine/threonine-protein kinase mTOR (Human)	BDBM36409 (CID24905147 | 2-(4-amino-1-isopropyl-1H-pyrazolo[3...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	410	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase mTOR (Human)	BDBM36409 (CID24905147 | 2-(4-amino-1-isopropyl-1H-pyrazolo[3...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform (Human)	BDBM36409 (CID24905147 | 2-(4-amino-1-isopropyl-1H-pyrazolo[3...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	120	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (Human)	BDBM36409 (CID24905147 | 2-(4-amino-1-isopropyl-1H-pyrazolo[3...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	42	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Human)	BDBM36409 (CID24905147 | 2-(4-amino-1-isopropyl-1H-pyrazolo[3...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	31	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Phosphatidylinositol 4-kinase beta (Human)	BDBM36409 (CID24905147 | 2-(4-amino-1-isopropyl-1H-pyrazolo[3...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	940	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (Human)	BDBM36409 (CID24905147 | 2-(4-amino-1-isopropyl-1H-pyrazolo[3...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	150	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Target of rapamycin complex subunit LST8 (Human)	BDBM36409 (CID24905147 | 2-(4-amino-1-isopropyl-1H-pyrazolo[3...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Target of rapamycin complex 2 subunit MAPKAP1 (Human)	BDBM36409 (CID24905147 | 2-(4-amino-1-isopropyl-1H-pyrazolo[3...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	80	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase mTOR (Human)	BDBM36409 (CID24905147 | 2-(4-amino-1-isopropyl-1H-pyrazolo[3...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase mTOR (Human)	BDBM36409 (CID24905147 | 2-(4-amino-1-isopropyl-1H-pyrazolo[3...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Target of rapamycin complex subunit LST8 (Human)	BDBM36409 (CID24905147 | 2-(4-amino-1-isopropyl-1H-pyrazolo[3...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	33	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Target of rapamycin complex subunit LST8 (Human)	BDBM36409 (CID24905147 | 2-(4-amino-1-isopropyl-1H-pyrazolo[3...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	320	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase mTOR (Human)	BDBM36409 (CID24905147 | 2-(4-amino-1-isopropyl-1H-pyrazolo[3...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (Human)	BDBM36409 (CID24905147 | 2-(4-amino-1-isopropyl-1H-pyrazolo[3...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform (Human)	BDBM36409 (CID24905147 | 2-(4-amino-1-isopropyl-1H-pyrazolo[3...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Human)	BDBM36409 (CID24905147 | 2-(4-amino-1-isopropyl-1H-pyrazolo[3...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (Human)	BDBM36409 (CID24905147 | 2-(4-amino-1-isopropyl-1H-pyrazolo[3...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Target of rapamycin complex subunit LST8 (Human)	BDBM36409 (CID24905147 | 2-(4-amino-1-isopropyl-1H-pyrazolo[3...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Target of rapamycin complex 2 subunit MAPKAP1 (Human)	BDBM36409 (CID24905147 | 2-(4-amino-1-isopropyl-1H-pyrazolo[3...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	58	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase mTOR (Human)	BDBM36409 (CID24905147 | 2-(4-amino-1-isopropyl-1H-pyrazolo[3...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase mTOR (Human)	BDBM36409 (CID24905147 | 2-(4-amino-1-isopropyl-1H-pyrazolo[3...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	142	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase mTOR (Human)	BDBM36409 (CID24905147 | 2-(4-amino-1-isopropyl-1H-pyrazolo[3...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	149	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase mTOR (Human)	BDBM36409 (CID24905147 | 2-(4-amino-1-isopropyl-1H-pyrazolo[3...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	418	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase mTOR (Human)	BDBM36409 (CID24905147 | 2-(4-amino-1-isopropyl-1H-pyrazolo[3...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	618	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase mTOR (Human)	BDBM36409 (CID24905147 | 2-(4-amino-1-isopropyl-1H-pyrazolo[3...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	247	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase mTOR (Human)	BDBM36409 (CID24905147 | 2-(4-amino-1-isopropyl-1H-pyrazolo[3...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	241	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair