BDBM364431 2-fluoro-5-(1-methyl-1H-pyrazol-3- yl)-N-(2-phenyl-2H-pyrazolo[4,3- b]pyridin-3-yl)-4- (trifluoromethyl)benzamide::US9862707, Example 5
SMILES Cn1ccc(n1)-c1cc(C(=O)Nc2n(nc3cccnc23)-c2ccccc2)c(F)cc1C(F)(F)F
InChI Key InChIKey=CMLHXMMFTDDLSH-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 364431
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
China Pharmaceutical University
Curated by ChEMBL
China Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 0.660nMAssay Description:Inhibition of recombinant full length human TRKA expressed in U2OS cells using Poly(Glu:Tyr) as substrate after 30 mins by scintillation counting ass...More data for this Ligand-Target Pair
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
China Pharmaceutical University
Curated by ChEMBL
China Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 0.660nMAssay Description:TrkA functional activity was measured using a DiscoverX PathHunter assay. In this assay, U2OS cells express the human TrkA receptor as a fusion with ...More data for this Ligand-Target Pair