BDBM364647 US9862730, Example 106

SMILES: COc1ccc2c(C)c(oc2c1)-c1cn2nc(SC)sc2n1

InChI Key: InChIKey=TZRSKOQWYJAJLU-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 364647   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Proteinase-activated receptor 4 (PAR4) (Homo sapiens (Human))	BDBM364647 (US9862730, Example 106) Show SMILES COc1ccc2c(C)c(oc2c1)-c1cn2nc(SC)sc2n1 Show InChI InChI=1S/C15H13N3O2S2/c1-8-10-5-4-9(19-2)6-12(10)20-13(8)11-7-18-14(16-11)22-15(17-18)21-3/h4-7H,1-3H3	Reactome pathway UniProtKB/SwissProt antibodypedia GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	13.9	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Co. US Patent					Assay Description The FLIPR assay is an exemplary in vitro assay for measuring the activity of the PAR4 antagonists of the present invention. In this assay, intracellu...				US Patent US9862730 (2018) BindingDB Entry DOI: 10.7270/Q2X92DKF
					More data for this Ligand-Target Pair