BDBM36486 9-Cyclopentyl-2-(2-ethoxy-4-(4-hydroxypiperidin-1-yl)phenylamino)-5-methyl-8,9-dihydro-5H-pyrimido[5,4-b][1,4]diazepin-6(7H)-one::Mps1-IN-2::Scaffold, B13::US9266890, I-10

SMILES: CCOc1cc(ccc1Nc1ncc2N(C)C(=O)CCN(C3CCCC3)c2n1)N1CCC(O)CC1

InChI Key: InChIKey=WELBJLUKWAJOQV-UHFFFAOYSA-N

Data: 3 IC50  2 Kd

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 36486   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dual specificity protein kinase TTK (Human)	BDBM36486 (US9266890, I-10 | Scaffold, B13 | 9-Cyclopentyl-2-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	145	n/a	n/a	n/a	n/a	7.5	0
TBA									Citation and Details
					More data for this Ligand-Target Pair
Dual specificity protein kinase TTK (Human)	BDBM36486 (US9266890, I-10 | Scaffold, B13 | 9-Cyclopentyl-2-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	145	26	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Dual specificity protein kinase TTK (Human)	BDBM36486 (US9266890, I-10 | Scaffold, B13 | 9-Cyclopentyl-2-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	145	n/a	n/a	n/a	n/a	n/a	25
TBA									Citation and Details
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase PLK1 (Human)	BDBM36486 (US9266890, I-10 | Scaffold, B13 | 9-Cyclopentyl-2-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	47	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair