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BDBM36571 EHR

SMILES: OC(CN(CCc1ccc2OCOc2c1)C(=O)CCN1C(=O)c2ccccc2C1=O)[C@@H](NC(=O)COc1cccc(Cl)c1)c1ccccc1

InChI Key: InChIKey=ANKGDJIGIZUTEH-KMYRUMMCNA-N

Data: 1 KI  1 IC50

Find this compound or compounds like it in BindingDB or PDB:
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 36571   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Cathepsin D


(Homo sapiens (Human))
BDBM36571
PNG
(EHR)
Show SMILES OC(CN(CCc1ccc2OCOc2c1)C(=O)CCN1C(=O)c2ccccc2C1=O)[C@@H](NC(=O)COc1cccc(Cl)c1)c1ccccc1
Show InChI InChI=1/C37H34ClN3O8/c38-26-9-6-10-27(20-26)47-22-33(43)39-35(25-7-2-1-3-8-25)30(42)21-40(17-15-24-13-14-31-32(19-24)49-23-48-31)34(44)16-18-41-36(45)28-11-4-5-12-29(28)37(41)46/h1-14,19-20,30,35,42H,15-18,21-23H2,(H,39,43)/t30?,35-/s2
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

B.MOAD
DrugBank
GoogleScholar
PC cid
PC sid
UniChem

Similars

Article
PubMed
15n/a 20n/an/an/an/a3.7n/a



University of California Berkeley



Assay Description
A fluorometric high through-put assay for inhibitor towards human liver cathepsin D from Calbiochem.


Chem Biol 4: 297-307 (1997)


Article DOI: 10.1007/s00210-003-0860-y
BindingDB Entry DOI: 10.7270/Q21R6NW9
More data for this
Ligand-Target Pair