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BDBM365752 1-(4-((3′-methoxy-2-methylbiphenyl-3-yl)methoxy)benzyl)azetidine::US9872852, Example 4

SMILES: COc1cccc(c1)-c1cccc(COc2ccc(CN3CCC3)cc2)c1C

InChI Key: InChIKey=XVXOHBUMANNZRJ-UHFFFAOYSA-N

Data: 1 IC50

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   Substructure
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 365752   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Programmed cell death 1 ligand 1


(Homo sapiens (Human))
BDBM365752
PNG
(1-(4-((3′-methoxy-2-methylbiphenyl-3-yl)meth...)
Show SMILES COc1cccc(c1)-c1cccc(COc2ccc(CN3CCC3)cc2)c1C
Show InChI InChI=1S/C25H27NO2/c1-19-22(7-4-9-25(19)21-6-3-8-24(16-21)27-2)18-28-23-12-10-20(11-13-23)17-26-14-5-15-26/h3-4,6-13,16H,5,14-15,17-18H2,1-2H3
PDB

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UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 5.51E+3n/an/an/an/an/an/a



Bristol-Myers Squibb Co.

US Patent


Assay Description
All binding studies were performed in an HTRF assay buffer consisting of dPBS supplemented with 0.1% (withv) bovine serum albumin and 0.05% (v/v) Twe...


US Patent US9872852 (2018)


BindingDB Entry DOI: 10.7270/Q2RN3B42
More data for this
Ligand-Target Pair