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BDBM365787 1-({3-[(2-methyl-3- phenylphenyl)methoxy]phenyl} methyl)azetidine::US9872852, Example 39

SMILES: Cc1c(COc2cccc(CN3CCC3)c2)cccc1-c1ccccc1

InChI Key: InChIKey=XQIVBIQDGUDOIA-UHFFFAOYSA-N

Data: 1 IC50

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   Substructure
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 365787   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Programmed cell death 1 ligand 1


(Homo sapiens (Human))
BDBM365787
PNG
(1-({3-[(2-methyl-3- phenylphenyl)methoxy]phenyl} m...)
Show SMILES Cc1c(COc2cccc(CN3CCC3)c2)cccc1-c1ccccc1
Show InChI InChI=1S/C24H25NO/c1-19-22(11-6-13-24(19)21-9-3-2-4-10-21)18-26-23-12-5-8-20(16-23)17-25-14-7-15-25/h2-6,8-13,16H,7,14-15,17-18H2,1H3
PDB

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UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 4.18E+3n/an/an/an/an/an/a



Bristol-Myers Squibb Co.

US Patent


Assay Description
All binding studies were performed in an HTRF assay buffer consisting of dPBS supplemented with 0.1% (withv) bovine serum albumin and 0.05% (v/v) Twe...


US Patent US9872852 (2018)


BindingDB Entry DOI: 10.7270/Q2RN3B42
More data for this
Ligand-Target Pair