BDBM365815 US9872852, Example 67::l-({3-bromo-4-[(2-methyl-3- phenylphenyl)methoxy]phenyl} methyl)azetidine

SMILES: Cc1c(COc2ccc(CN3CCC3)cc2Br)cccc1-c1ccccc1

InChI Key: InChIKey=PRRWLKVPTPBWHS-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 365815   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Programmed cell death 1 ligand 1 (Homo sapiens (Human))	BDBM365815 (US9872852, Example 67 | l-({3-bromo-4-[(2-methyl-3...) Show SMILES Cc1c(COc2ccc(CN3CCC3)cc2Br)cccc1-c1ccccc1 Show InChI InChI=1S/C24H24BrNO/c1-18-21(9-5-10-22(18)20-7-3-2-4-8-20)17-27-24-12-11-19(15-23(24)25)16-26-13-6-14-26/h2-5,7-12,15H,6,13-14,16-17H2,1H3	PDB Reactome pathway UniProtKB/SwissProt GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	555	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Co. US Patent					Assay Description All binding studies were performed in an HTRF assay buffer consisting of dPBS supplemented with 0.1% (withv) bovine serum albumin and 0.05% (v/v) Twe...				US Patent US9872852 (2018) BindingDB Entry DOI: 10.7270/Q2RN3B42
					More data for this Ligand-Target Pair