BindingDB logo
myBDB logout

BDBM365815 US9872852, Example 67::l-({3-bromo-4-[(2-methyl-3- phenylphenyl)methoxy]phenyl} methyl)azetidine

SMILES: Cc1c(COc2ccc(CN3CCC3)cc2Br)cccc1-c1ccccc1

InChI Key: InChIKey=PRRWLKVPTPBWHS-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 365815   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Programmed cell death 1 ligand 1


(Homo sapiens (Human))
BDBM365815
PNG
(US9872852, Example 67 | l-({3-bromo-4-[(2-methyl-3...)
Show SMILES Cc1c(COc2ccc(CN3CCC3)cc2Br)cccc1-c1ccccc1
Show InChI InChI=1S/C24H24BrNO/c1-18-21(9-5-10-22(18)20-7-3-2-4-8-20)17-27-24-12-11-19(15-23(24)25)16-26-13-6-14-26/h2-5,7-12,15H,6,13-14,16-17H2,1H3
PDB

Reactome pathway

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 555n/an/an/an/an/an/a



Bristol-Myers Squibb Co.

US Patent


Assay Description
All binding studies were performed in an HTRF assay buffer consisting of dPBS supplemented with 0.1% (withv) bovine serum albumin and 0.05% (v/v) Twe...


US Patent US9872852 (2018)


BindingDB Entry DOI: 10.7270/Q2RN3B42
More data for this
Ligand-Target Pair