BDBM366816 US9873709, Example 2-110::ethyl 4-[2-[4-[(1,1- dimethyl-2- morpholino- ethyl)carbamoyl]anilino]- [1,2,4]triazolo[1,5- a]pyridin-8-yl]-3,6- dihydro-2H-pyridine- 1-carboxylate

SMILES CCOC(=O)N1CCC(=CC1)c1cccn2nc(Nc3ccc(cc3)C(=O)NC(C)(C)CN3CCOCC3)nc12

InChI Key InChIKey=BXVWXSTZIBCXPO-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 366816   

TargetTyrosine-protein kinase JAK1(Human)
Genentech

US Patent
LigandPNGBDBM366816(ethyl 4-[2-[4-[(1,1- dimethyl-2- morpholino- ethyl...)
Affinity DataKi:  3.27nMAssay Description:The activity of the isolated recombinant JAK1 and JAK2 kinase domain was measured by monitoring phosphorylation of a peptide derived from JAK3 (Val-A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2019
Entry Details
US Patent