BDBM367400 US10227299, Example 90::tert-Butyl (2S)-2-([(6RS)-4-oxo-3-(phenylamino)-2-(pyridin-4-yl)-4,5,6,7-tetrahydro-1H-indol-6-yl]methylcarbamoyl)pyrrolidine-1-carboxylate

SMILES CC(C)(C)OC(=O)N1CCCC1C(=O)NCC1Cc2[nH]c(c(Nc3ccccc3)c2C(=O)C1)-c1ccncc1

InChI Key InChIKey=WDXWGGFNAUVZQR-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 367400   

TargetMitotic checkpoint serine/threonine-protein kinase BUB1(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM367400(tert-Butyl (2S)-2-([(6RS)-4-oxo-3-(phenylamino)-2-...)
Affinity DataIC50: 232nMAssay Description:Bub1-inhibitory activities of compounds described in the present invention were quantified using a time-resolved fluorescence energy transfer (TR-FRE...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent