BDBM367404 N-4-[(6RS)-6-(Hydroxymethyl)-4-oxo-3-(phenylamino)-4,5,6,7-tetrahydro-1H-indol-2-yl]pyridin-2-ylacetamide::US10227299, Example 94

SMILES CC(=O)Nc1cc(ccn1)-c1[nH]c2CC(CO)CC(=O)c2c1Nc1ccccc1

InChI Key InChIKey=XKXPEJQATWSJME-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 367404   

TargetMitotic checkpoint serine/threonine-protein kinase BUB1(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM367404(N-4-[(6RS)-6-(Hydroxymethyl)-4-oxo-3-(phenylamino)...)
Affinity DataIC50: 15nMAssay Description:Bub1-inhibitory activities of compounds described in the present invention were quantified using a time-resolved fluorescence energy transfer (TR-FRE...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent