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BDBM367670 Synthesis of (S)-2-amino-N-(methylsulfonyl)pent-4-ynamide hydrochloride ::US10227314, Example 9

SMILES: CS(=O)(=O)NC(=O)[C@@H](N)CC#C

InChI Key: InChIKey=PHFDNKAMFHABRE-YFKPBYRVSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 367670   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Cystathionine gamma-lyase


(Homo sapiens (Human))
BDBM367670
PNG
(Synthesis of (S)-2-amino-N-(methylsulfonyl)pent-4-...)
Show SMILES CS(=O)(=O)NC(=O)[C@@H](N)CC#C
Show InChI InChI=1S/C6H10N2O3S/c1-3-4-5(7)6(9)8-12(2,10)11/h1,5H,4,7H2,2H3,(H,8,9)/t5-/m0/s1
PDB
MMDB

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PC cid
PC sid
UniChem
US Patent
n/an/a 1.25E+5n/an/an/an/an/an/a



SOVA PHARMACEUTICALS, INC.

US Patent


Assay Description
Test compounds (from DMSO stock solutions) were added to (final concentrations) 20 ug/ml enzyme solution (human, mouse or rat recombinant CSE) plus 5...


US Patent US10227314 (2019)


BindingDB Entry DOI: 10.7270/Q2BC41T6
More data for this
Ligand-Target Pair