BDBM369343 N-[1-[6-(1,3-dimethylpyrazol-4-yl)-7H- pyrrolo[2,3-d]pyrimidin-4-yl]-4- piperidyl]-4-methyl- benzenesulfonamide::US10227357, Compound P-0659

SMILES Cc1nn(C)cc1-c1cc2c(ncnc2[nH]1)N1CCC(CC1)NS(=O)(=O)c1ccc(C)cc1

InChI Key InChIKey=ULLMBBXJQUJFPA-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 369343   

TargetMast/stem cell growth factor receptor Kit [D816V](Homo sapiens (Human))
Plexxikon

US Patent
LigandPNGBDBM369343(N-[1-[6-(1,3-dimethylpyrazol-4-yl)-7H- pyrrolo[2,3...)
Affinity DataKi:  500nMAssay Description:The c-Kit mutant D816V inhibitors were assessed using an engineered BaF3-FL KIT D816V or BaF3-FL KIT V560G/D816V cell line. The BaF3-FL KIT D816V cel...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent