BDBM369354 N-[1-[6-(4-chloro-2-thienyl)-7H- pyrrolo[2,3-d]pyrimidin-4-yl]-4- piperidyl]-4- (trifluoromethoxy)benzenesulfonamide::US10227357, Compound P-0670

SMILES FC(F)(F)Oc1ccc(cc1)S(=O)(=O)NC1CCN(CC1)c1ncnc2[nH]c(cc12)-c1cc(Cl)cs1

InChI Key InChIKey=AWYANESNMMTKNS-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 369354   

TargetMast/stem cell growth factor receptor Kit(Human)
Plexxikon

US Patent
LigandPNGBDBM369354(N-[1-[6-(4-chloro-2-thienyl)-7H- pyrrolo[2,3-d]pyr...)
Affinity DataKi:  1.05E+5nMAssay Description:The c-Kit mutant D816V inhibitors were assessed using an engineered BaF3-FL KIT D816V or BaF3-FL KIT V560G/D816V cell line. The BaF3-FL KIT D816V cel...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent