BDBM369386 4-[6-(4-fluorophenyl)thieno[3,2- d]pyrimidin-4-yl]-N-[1-(5-methyl-2- thienyl)ethyl]piperazine-1-carboxamide::US10227357, Compound P-0703

SMILES CC(NC(=O)N1CCN(CC1)c1ncnc2cc(sc12)-c1ccc(F)cc1)c1ccc(C)s1

InChI Key InChIKey=RGMZMROOQGKZFI-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 369386   

TargetMast/stem cell growth factor receptor Kit [D816V](Homo sapiens (Human))
Plexxikon

US Patent
LigandPNGBDBM369386(4-[6-(4-fluorophenyl)thieno[3,2- d]pyrimidin-4-yl]...)
Affinity DataKi:  500nMAssay Description:The c-Kit mutant D816V inhibitors were assessed using an engineered BaF3-FL KIT D816V or BaF3-FL KIT V560G/D816V cell line. The BaF3-FL KIT D816V cel...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent