BDBM369387 5-[6-(1,3-dimethylpyrazol-4-yl)thieno[3,2- d]pyrimidin-4-yl]-N-[(1R)-1-(4- fluorophenyl)ethyl]-2,5- diazabicyclo[2.2.2]octane-2-carboxamide::US10227357, Compound P-0704

SMILES C[C@@H](NC(=O)N1CC2CCC1CN2c1ncnc2cc(sc12)-c1cn(C)nc1C)c1ccc(F)cc1

InChI Key InChIKey=RSNCJBWVILSCSB-APMMTJHUSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 369387   

TargetMast/stem cell growth factor receptor Kit [D816V](Homo sapiens (Human))
Plexxikon

US Patent
LigandPNGBDBM369387(5-[6-(1,3-dimethylpyrazol-4-yl)thieno[3,2- d]pyrim...)
Affinity DataKi:  500nMAssay Description:The c-Kit mutant D816V inhibitors were assessed using an engineered BaF3-FL KIT D816V or BaF3-FL KIT V560G/D816V cell line. The BaF3-FL KIT D816V cel...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent