BDBM370810 US10238633, Example 240

SMILES Fc1cc(ccc1C[C@H](NC(=O)[C@H]1N[C@@H]2CC[C@H]1C2)C#N)-c1cc(co1)C(=O)N1CCC2N=CC=C2C1

InChI Key InChIKey=IBKXVVFDLAEVPN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 370810   

TargetDipeptidyl peptidase 1(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM370810(US10238633, Example 240)
Affinity DataIC50: 6.10nMAssay Description:The recombinant human DPPI was diluted in TAGZyme buffer to 1 U/ml (38.1 μg/ml, respectively), and then activated by mixing in a 1:2 ratio with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
US Patent

TargetCathepsin K(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM370810(US10238633, Example 240)
Affinity DataIC50: 9.40E+3nMAssay Description:To activate the proenzyme, 5 μl procathepsin K were mixed with 1 ul activation buffer, and incubated at room temperature for 30 min.5 μL te...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
US Patent