BDBM37088 2-[(3,6-dimethyl-4-oxidanylidene-6,7-dihydrothieno[3,2-d]pyrimidin-2-yl)sulfanyl]-N-(6-methyl-1,3-benzothiazol-2-yl)ethanamide::2-[(3,6-dimethyl-4-oxo-3,4,6,7-tetrahydrothieno[3,2-d]pyrimidin-2-yl)thio]-N-(6-methyl-1,3-benzothiazol-2-yl)acetamide::2-[(3,6-dimethyl-4-oxo-6,7-dihydrothieno[3,2-d]pyrimidin-2-yl)sulfanyl]-N-(6-methyl-1,3-benzothiazol-2-yl)acetamide::2-[(3,6-dimethyl-4-oxo-6,7-dihydrothieno[3,2-d]pyrimidin-2-yl)thio]-N-(6-methyl-1,3-benzothiazol-2-yl)acetamide::2-[(4-keto-3,6-dimethyl-6,7-dihydrothieno[3,2-d]pyrimidin-2-yl)thio]-N-(6-methyl-1,3-benzothiazol-2-yl)acetamide::MLS000091043::SMR000025621::cid_3244448

SMILES CC1Cc2nc(SCC(=O)Nc3nc4ccc(C)cc4s3)n(C)c(=O)c2S1

InChI Key InChIKey=RBFDSBJDWZOTGR-UHFFFAOYSA-N

Data  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 37088   

TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM37088(2-[(3,6-dimethyl-4-oxidanylidene-6,7-dihydrothieno...)
Affinity DataEC50:  1.65E+4nMAssay Description:Source (MLSCN Center Name): The Scripps Research Institute Molecular Screening Center Center Affiliation: The Scripps Research Institute, TSRI Assay ...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetProtein-serine O-palmitoleoyltransferase porcupine(Mus musculus)
The University Of Texas Southwestern Medical Center

Curated by ChEMBL
LigandPNGBDBM37088(2-[(3,6-dimethyl-4-oxidanylidene-6,7-dihydrothieno...)
Affinity DataEC50:  15nMAssay Description:Inhibition of porcupine-mediated Wnt signalling in mouse L cells after 24 hrs by SpringerImages-Topflash reporter assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM37088(2-[(3,6-dimethyl-4-oxidanylidene-6,7-dihydrothieno...)
Affinity DataEC50:  1.32E+4nMAssay Description:Source (MLSCN Center Name): The Scripps Research Institute Molecular Screening Center Center Affiliation: The Scripps Research Institute, TSRI Assay ...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM37088(2-[(3,6-dimethyl-4-oxidanylidene-6,7-dihydrothieno...)
Affinity DataEC50: >9.51E+4nMAssay Description:Source (MLSCN Center Name): The Scripps Research Institute Molecular Screening Center Center Affiliation: The Scripps Research Institute, TSRI Assay ...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay