BDBM371441 N-[1-(Fluoromethyl)cyclopropyl]-3-[(3-methylisoxazol-5-yl)methyl]-1-[(2-methylthiazol-4-yl)methyl]-2,4-dioxo-quinazoline-6-sulfonamide::US10239843, Example 550

SMILES Cc1cc(Cn2c(=O)n(Cc3csc(C)n3)c3ccc(cc3c2=O)S(=O)(=O)NC2(CF)CC2)on1

InChI Key InChIKey=SEDKEVZISKHOGC-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 371441   

TargetPoly(ADP-ribose) glycohydrolase(Homo sapiens (Human))
Cancer Research Technology

US Patent
LigandPNGBDBM371441(N-[1-(Fluoromethyl)cyclopropyl]-3-[(3-methylisoxaz...)
Affinity DataIC50:  191nMAssay Description:PARG In vitro assays were conducted in a total volume of 15 ul in a standard 384 well format. 5 ul of Human Full Length PARG (Produced internally by ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent