BDBM371881 US10239870, Example 98

SMILES: Cn1c(SCCCN2CC[C@@]3(C[C@H]3c3ccc(cc3)C(F)(F)F)C2)nnc1C1CCCCC1

InChI Key: InChIKey=CTRVTEOXKBMCKO-XUZZJYLKSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 371881   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dopamine receptor D2 and D3 (Rattus norvegicus (Rat))	BDBM371881 (US10239870, Example 98) Show SMILES Cn1c(SCCCN2CC[C@@]3(C[C@H]3c3ccc(cc3)C(F)(F)F)C2)nnc1C1CCCCC1 Show InChI InChI=1S/C25H33F3N4S/c1-31-22(19-6-3-2-4-7-19)29-30-23(31)33-15-5-13-32-14-12-24(17-32)16-21(24)18-8-10-20(11-9-18)25(26,27)28/h8-11,19,21H,2-7,12-17H2,1H3/t21-,24+/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar	PC cid PC sid UniChem	US Patent	31.6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Indivior UK Limited US Patent					Assay Description [125I]-7OH-PIPAT Binding Assay at rat native D3 receptor on membranes from rat ventral striatum. Homogenates from frozen rat brain ventral striatum (...				US Patent US10239870 (2019) BindingDB Entry DOI: 10.7270/Q2HT2RNX
					More data for this Ligand-Target Pair