BDBM372275 8-methyl-4- (pyrrolidin-1-yl) pyrido[3',2':4,5]thieno [3,2-d]pyrimidine::US10239887, Cpd. No. 15

SMILES: Cc1cnc2sc3c(ncnc3c2c1)N1CCCC1

InChI Key: InChIKey=WNVHONNDYZZMQU-UHFFFAOYSA-N

Data: 2 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 372275   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Muscarinic acetylcholine receptor M4 (RAT)	BDBM372275 (8-methyl-4- (pyrrolidin-1-yl) pyrido[3',2':4,5]thi...) Show SMILES Cc1cnc2sc3c(ncnc3c2c1)N1CCCC1 Show InChI InChI=1S/C14H14N4S/c1-9-6-10-11-12(19-14(10)15-7-9)13(17-8-16-11)18-4-2-3-5-18/h6-8H,2-5H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
Vanderbilt University US Patent					Assay Description For high throughput measurement of agonist-evoked increases in intracellular calcium, CHO-K1 cells stably expressing muscarinic receptors were plated...				US Patent US10239887 (2019) BindingDB Entry DOI: 10.7270/Q2W09880
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M4 (Homo sapiens (Human))	BDBM372275 (8-methyl-4- (pyrrolidin-1-yl) pyrido[3',2':4,5]thi...) Show SMILES Cc1cnc2sc3c(ncnc3c2c1)N1CCCC1 Show InChI InChI=1S/C14H14N4S/c1-9-6-10-11-12(19-14(10)15-7-9)13(17-8-16-11)18-4-2-3-5-18/h6-8H,2-5H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	161	n/a	n/a	n/a	n/a
Vanderbilt University US Patent					Assay Description For high throughput measurement of agonist-evoked increases in intracellular calcium, CHO-K1 cells stably expressing muscarinic receptors were plated...				US Patent US10239887 (2019) BindingDB Entry DOI: 10.7270/Q2W09880
					More data for this Ligand-Target Pair