BDBM37260 (2,2,4-trimethyl-3,4-dihydro-1H-quinolin-6-yl) furan-2-carboxylate::2-furancarboxylic acid (2,2,4-trimethyl-3,4-dihydro-1H-quinolin-6-yl) ester::MLS000113523::SMR000109421::cid_2927276::furan-2-carboxylic acid (2,2,4-trimethyl-3,4-dihydro-1H-quinolin-6-yl) ester

SMILES CC1CC(C)(C)Nc2ccc(OC(=O)c3ccco3)cc12

InChI Key InChIKey=CVNMNGDFYKHBRQ-UHFFFAOYSA-N

Data  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 37260   

TargetMatrix metalloproteinase-14 [1-36](Human)
Sanford-Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM37260((2,2,4-trimethyl-3,4-dihydro-1H-quinolin-6-yl) fur...)
Affinity DataEC50:  3.01E+3nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/30/2011
Entry Details
PCBioAssay
TargetSphingosine 1-phosphate receptor 1(Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM37260((2,2,4-trimethyl-3,4-dihydro-1H-quinolin-6-yl) fur...)
Affinity DataEC50:  7.66E+3nMAssay Description:Source (MLSCN Center Name): The Scripps Research Institute Molecular Screening Center Center Affiliation: The Scripps Research Institute, TSRI Assay ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/28/2011
Entry Details
PCBioAssay
TargetSphingosine 1-phosphate receptor 1(Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM37260((2,2,4-trimethyl-3,4-dihydro-1H-quinolin-6-yl) fur...)
Affinity DataEC50:  1.36E+4nMAssay Description:Source (MLSCN Center Name): The Scripps Research Institute Molecular Screening Center Center Affiliation: The Scripps Research Institute, TSRI Assay ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2011
Entry Details
PCBioAssay
TargetSphingosine 1-phosphate receptor 1(Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM37260((2,2,4-trimethyl-3,4-dihydro-1H-quinolin-6-yl) fur...)
Affinity DataEC50:  1.40E+4nMAssay Description:Source (MLSCN Center Name): The Scripps Research Institute Molecular Screening Center Center Affiliation: The Scripps Research Institute, TSRI Assay ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/28/2011
Entry Details
PCBioAssay