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BDBM37275 4-[3-(2-methylphenyl)-2H-1,2,4-oxadiazol-5-ylidene]-1-cyclohexa-2,5-dienone::4-[3-(2-methylphenyl)-2H-1,2,4-oxadiazol-5-ylidene]cyclohexa-2,5-dien-1-one::4-[3-(o-tolyl)-2H-1,2,4-oxadiazol-5-ylidene]cyclohexa-2,5-dien-1-one::MLS000112501::SMR000108415::cid_5407960

SMILES: Cc1ccccc1-c1noc(n1)-c1ccc(O)cc1

InChI Key: InChIKey=ZMXAKACKYKVMGO-UHFFFAOYSA-N

Data: 2 IC50  4 EC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 37275   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Sphingosine 1-phosphate receptor


(Homo sapiens (Human))
BDBM37275
PNG
(4-[3-(2-methylphenyl)-2H-1,2,4-oxadiazol-5-ylidene...)
Show SMILES Cc1ccccc1-c1noc(n1)-c1ccc(O)cc1
Show InChI InChI=1S/C15H12N2O2/c1-10-4-2-3-5-13(10)14-16-15(19-17-14)11-6-8-12(18)9-7-11/h2-9,18H,1H3
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n/an/an/an/a 8.25E+3n/an/an/an/a



The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay


Assay Description
Source (MLSCN Center Name): The Scripps Research Institute Molecular Screening Center Center Affiliation: The Scripps Research Institute, TSRI Assay ...


PubChem Bioassay (2007)


BindingDB Entry DOI: 10.7270/Q2ZC817P
More data for this
Ligand-Target Pair
Sphingosine 1-phosphate receptor


(Homo sapiens (Human))
BDBM37275
PNG
(4-[3-(2-methylphenyl)-2H-1,2,4-oxadiazol-5-ylidene...)
Show SMILES Cc1ccccc1-c1noc(n1)-c1ccc(O)cc1
Show InChI InChI=1S/C15H12N2O2/c1-10-4-2-3-5-13(10)14-16-15(19-17-14)11-6-8-12(18)9-7-11/h2-9,18H,1H3
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n/an/an/an/a 2.50E+4n/an/an/an/a



The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay


Assay Description
Source (MLSCN Center Name): The Scripps Research Institute Molecular Screening Center Center Affiliation: The Scripps Research Institute, TSRI Assay ...


PubChem Bioassay (2007)


BindingDB Entry DOI: 10.7270/Q25X2795
More data for this
Ligand-Target Pair
ADAM17


(Homo sapiens (Human))
BDBM37275
PNG
(4-[3-(2-methylphenyl)-2H-1,2,4-oxadiazol-5-ylidene...)
Show SMILES Cc1ccccc1-c1noc(n1)-c1ccc(O)cc1
Show InChI InChI=1S/C15H12N2O2/c1-10-4-2-3-5-13(10)14-16-15(19-17-14)11-6-8-12(18)9-7-11/h2-9,18H,1H3
PDB
MMDB

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n/an/a 6.95E+4n/an/an/an/an/an/a



The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay


Assay Description
Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Center Affiliation: Torrey Pines Institute for Molecul...


PubChem Bioassay (2014)


BindingDB Entry DOI: 10.7270/Q21J98DJ
More data for this
Ligand-Target Pair
Nuclear factor NF-kappa-B


(Homo sapiens (Human))
BDBM37275
PNG
(4-[3-(2-methylphenyl)-2H-1,2,4-oxadiazol-5-ylidene...)
Show SMILES Cc1ccccc1-c1noc(n1)-c1ccc(O)cc1
Show InChI InChI=1S/C15H12N2O2/c1-10-4-2-3-5-13(10)14-16-15(19-17-14)11-6-8-12(18)9-7-11/h2-9,18H,1H3
PDB

KEGG

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n/an/an/an/a 6.21E+3n/an/an/an/a



SRMLSC

Curated by PubChem BioAssay


Assay Description
Southern Research Molecular Libraries Screening Center (SRMLSC) Southern Research Institute (Birmingham, Alabama) NIH Molecular Libraries Screening C...


PubChem Bioassay (2008)


BindingDB Entry DOI: 10.7270/Q27P8WT7
More data for this
Ligand-Target Pair
Disintegrin and metalloproteinase domain-containing protein 10 (ADAM10)


(Homo sapiens (Human))
BDBM37275
PNG
(4-[3-(2-methylphenyl)-2H-1,2,4-oxadiazol-5-ylidene...)
Show SMILES Cc1ccccc1-c1noc(n1)-c1ccc(O)cc1
Show InChI InChI=1S/C15H12N2O2/c1-10-4-2-3-5-13(10)14-16-15(19-17-14)11-6-8-12(18)9-7-11/h2-9,18H,1H3
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n/an/a 4.88E+4n/an/an/an/an/an/a



The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay


Assay Description
Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Center Affiliation: Torrey Pines Institute for Molecul...


PubChem Bioassay (2014)


BindingDB Entry DOI: 10.7270/Q25B013C
More data for this
Ligand-Target Pair
Sphingosine 1-phosphate receptor


(Homo sapiens (Human))
BDBM37275
PNG
(4-[3-(2-methylphenyl)-2H-1,2,4-oxadiazol-5-ylidene...)
Show SMILES Cc1ccccc1-c1noc(n1)-c1ccc(O)cc1
Show InChI InChI=1S/C15H12N2O2/c1-10-4-2-3-5-13(10)14-16-15(19-17-14)11-6-8-12(18)9-7-11/h2-9,18H,1H3
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n/an/an/an/a 8.46E+3n/an/an/an/a



The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay


Assay Description
Source (MLSCN Center Name): The Scripps Research Institute Molecular Screening Center Center Affiliation: The Scripps Research Institute, TSRI Assay ...


PubChem Bioassay (2007)


BindingDB Entry DOI: 10.7270/Q2251GJ9
More data for this
Ligand-Target Pair