BDBM372994 US10597366, Compound 74::US9896418, Compound 74

SMILES: c1cc(c(c(c1Oc2cc(cc(c2)Cl)F)Br)CO)S(=O)(=O)C(F)F

InChI Key: InChIKey=GREQBABHNZHCOV-UHFFFAOYSA-N

Data: 2 IC50  4 EC50

PDB links: 1 PDB ID matches this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 372994   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Vascular endothelial growth factor A (Human)	BDBM372994 (US9896418, Compound 74 | US10597366, Compound 74) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	320	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Vascular endothelial growth factor A (Human)	BDBM372994 (US9896418, Compound 74 | US10597366, Compound 74) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	320	n/a	n/a	n/a	n/a
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Endothelial PAS domain-containing protein 1 (Human)	BDBM372994 (US9896418, Compound 74 | US10597366, Compound 74) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	150	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Vascular endothelial growth factor A (Human)	BDBM372994 (US9896418, Compound 74 | US10597366, Compound 74) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	320	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Endothelial PAS domain-containing protein 1 (Human)	BDBM372994 (US9896418, Compound 74 | US10597366, Compound 74) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	55	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Endothelial PAS domain-containing protein 1 (Human)	BDBM372994 (US9896418, Compound 74 | US10597366, Compound 74) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	330	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair