BDBM373514 (2-fluoro-3-methoxy-6-(2H-1,2,3-triazol-2-yl)phenyl)((2S,3R)-3-methyl-2-(((5-(trifluoromethyl)pyridin-2-yl)amino)methyl)piperidin-1-yl)methanone::US9896452, Ex. A338

SMILES COc1ccc(c(C(=O)N2CCC[C@@H](C)[C@H]2CNc2ccc(cn2)C(F)(F)F)c1F)-n1nccn1

InChI Key InChIKey=NMRYDMKXCPNLQL-RHSMWYFYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 373514   

TargetOrexin receptor type 2(Homo sapiens (Human))
Eolas Therapeutics

US Patent
LigandPNGBDBM373514((2-fluoro-3-methoxy-6-(2H-1,2,3-triazol-2-yl)pheny...)
Affinity DataIC50: >5.00E+3nMAssay Description:Measurement of [Ca2+]i using a FLIPR: CHO-OX1 or CHO-OX2 cells are seeded into black-walled clear-base 384-well plates (Costar) at a density of 20,00...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetOrexin/Hypocretin receptor type 1(Homo sapiens (Human))
Eolas Therapeutics

US Patent
LigandPNGBDBM373514((2-fluoro-3-methoxy-6-(2H-1,2,3-triazol-2-yl)pheny...)
Affinity DataIC50: <10nMAssay Description:Measurement of [Ca2+]i using a FLIPR: CHO-OX1 or CHO-OX2 cells are seeded into black-walled clear-base 384-well plates (Costar) at a density of 20,00...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent