BDBM374430 5-(1-(4-methylpyridin-2-yl)-1H-indazol-6-yl)pyridin-3-amine::US10246456, Example 39::US10577367, Example 39

SMILES Cc1ccnc(c1)-n1ncc2ccc(cc12)-c1cncc(N)c1

InChI Key InChIKey=DWKAHYYWXQZGJQ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 374430   

TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Biogen Ma

US Patent
LigandPNGBDBM374430(5-(1-(4-methylpyridin-2-yl)-1H-indazol-6-yl)pyridi...)
Affinity DataIC50:  550nMAssay Description:The biochemical assay is in a AlphaScreen format. The kinase reaction is based on the IRAK-4 phosphorylation of a biotin labeled peptide. The phospho...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Biogen Ma

US Patent
LigandPNGBDBM374430(5-(1-(4-methylpyridin-2-yl)-1H-indazol-6-yl)pyridi...)
Affinity DataIC50:  550nMAssay Description:The biochemical assay is in a AlphaScreen format. The kinase reaction is based on the IRAK-4 phosphorylation of a biotin labeled peptide. The phospho...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent