BDBM374640 1-((R)-1-(2,4-Dichlorophenyl)ethyl)-3-methyl-6-(3-methyl-4-((S)-2-methylpyrrolidin-1-yl)piperidin-1-yl)-1H-pyrazolo[3,4-b]pyrazine hydrochloride::US10246462, Example 21

SMILES C[C@H](c1ccc(Cl)cc1Cl)n1nc(C)c2ncc(nc12)N1CCC(C(C)C1)N1CCC[C@@H]1C

InChI Key InChIKey=MHYORVPBRVOLMW-PVEYFEBJSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 374640   

TargetC-C chemokine receptor type 4(Homo sapiens (Human))
Flx Bio

US Patent
LigandPNGBDBM374640(1-((R)-1-(2,4-Dichlorophenyl)ethyl)-3-methyl-6-(3-...)
Affinity DataIC50: >500nMAssay Description:To measure binding of 125I-TARC or 125I-MDC to cells expressing CCR4 (e.g., CEM cells (e.g., ATCC HB-12624)), the 125I-TARC or 125I-MDC is diluted to...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent