BDBM374945 2-(2',3-dimethyl-2,4'-bipyridin-5-yl)-N-(5-(pyrazin-2-yl)pyridin-2-yl)acetamide ::US10251893, Cpd 145

SMILES Cc1cc(ccn1)-c1ncc(CC(=O)Nc2ccc(cn2)-c2cccnn2)cc1C

InChI Key InChIKey=JGFUHALYZNHREH-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 374945   

TargetProtein Wnt-3a(Human)
Novartis

US Patent
LigandPNGBDBM374945(2-(2',3-dimethyl-2,4'-bipyridin-5-yl)-N-(5-(pyrazi...)
Affinity DataIC50: 1nMAssay Description:Human embryonic kidney 293 cells (obtained from American Type Culture Collection, ATCC, Manassas, Va.) are cultured in DMEM medium (Gibco/Invitrogen,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/21/2020
Entry Details
US Patent