BDBM374998 N-(5-(4-acetylpiperazin-1-yl)pyridin-2-yl)-2-(2'-fluoro-3-methyl-2,4'-bipyridin-5-yl)acetamide ::US10251893, Cpd 193

SMILES: CC(=O)N1CCN(CC1)c1ccc(NC(=O)Cc2cnc(c(C)c2)-c2ccnc(F)c2)nc1

InChI Key: InChIKey=AXXNRMISICMFNS-UHFFFAOYSA-N

Data: 9 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 374998   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein Wnt-3a (Human)	BDBM374998 (N-(5-(4-acetylpiperazin-1-yl)pyridin-2-yl)-2-(2'-f...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.100	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 2D6 (Human)	BDBM374998 (N-(5-(4-acetylpiperazin-1-yl)pyridin-2-yl)-2-(2'-f...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 2C9 (Human)	BDBM374998 (N-(5-(4-acetylpiperazin-1-yl)pyridin-2-yl)-2-(2'-f...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 3A4 (Human)	BDBM374998 (N-(5-(4-acetylpiperazin-1-yl)pyridin-2-yl)-2-(2'-f...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 2C9 (Human)	BDBM374998 (N-(5-(4-acetylpiperazin-1-yl)pyridin-2-yl)-2-(2'-f...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Protein-serine O-palmitoleoyltransferase porcupine (Mouse)	BDBM374998 (N-(5-(4-acetylpiperazin-1-yl)pyridin-2-yl)-2-(2'-f...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.800	n/a	n/a	n/a	n/a	n/a	n/a
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Protein-serine O-palmitoleoyltransferase porcupine (Mouse)	BDBM374998 (N-(5-(4-acetylpiperazin-1-yl)pyridin-2-yl)-2-(2'-f...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.800	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 3A4 (Human)	BDBM374998 (N-(5-(4-acetylpiperazin-1-yl)pyridin-2-yl)-2-(2'-f...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Cytochrome P450 2D6 (Human)	BDBM374998 (N-(5-(4-acetylpiperazin-1-yl)pyridin-2-yl)-2-(2'-f...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair