BDBM375018 2-(3-cyano-4-(2-fluoropyridin-4-yl)phenyl)-N-(5-(pyridazin-3-yl)pyridin-2-yl)acetamide ::US10251893, Cpd 214

SMILES Fc1cc(ccn1)-c1ccc(CC(=O)Nc2ccc(cn2)-c2cccnn2)cc1C#N

InChI Key InChIKey=HLHWQPZZOSUYSF-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 375018   

TargetProtein Wnt-3a(Human)
Novartis

US Patent
LigandPNGBDBM375018(2-(3-cyano-4-(2-fluoropyridin-4-yl)phenyl)-N-(5-(p...)
Affinity DataIC50: 0.200nMAssay Description:Human embryonic kidney 293 cells (obtained from American Type Culture Collection, ATCC, Manassas, Va.) are cultured in DMEM medium (Gibco/Invitrogen,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/21/2020
Entry Details
US Patent