BDBM375544 4-(6-(4-(morpholine-4-carbonyl)phenyl)imidazo[1,2-a]pyridin-3-yl)benzonitrile::US9908886, Example 96

SMILES: O=C(N1CCOCC1)c1ccc(cc1)-c1ccc2ncc(-c3ccc(cc3)C#N)n2c1

InChI Key: InChIKey=FWRFPHJSGLYXTD-UHFFFAOYSA-N

Data: 17 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 17 hits for monomerid = 375544   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
MAP kinase-interacting serine/threonine-protein kinase 2 (Human)	BDBM375544 (US9908886, Example 96 | 4-(6-(4-(morpholine-4-carb...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	86	n/a	n/a	n/a	n/a	n/a	n/a
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Eukaryotic translation initiation factor 4E (Human)	BDBM375544 (US9908886, Example 96 | 4-(6-(4-(morpholine-4-carb...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	646	n/a	n/a	n/a	n/a	n/a	n/a
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MAP kinase-interacting serine/threonine-protein kinase 2 (Human)	BDBM375544 (US9908886, Example 96 | 4-(6-(4-(morpholine-4-carb...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	24	n/a	n/a	n/a	n/a	n/a	n/a
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MAP kinase-interacting serine/threonine-protein kinase 1 (Human)	BDBM375544 (US9908886, Example 96 | 4-(6-(4-(morpholine-4-carb...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	22	n/a	n/a	n/a	n/a	n/a	n/a
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Eukaryotic translation initiation factor 4E (Human)	BDBM375544 (US9908886, Example 96 | 4-(6-(4-(morpholine-4-carb...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	321	n/a	n/a	n/a	n/a	n/a	n/a
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MAP kinase-interacting serine/threonine-protein kinase 2 (Human)	BDBM375544 (US9908886, Example 96 | 4-(6-(4-(morpholine-4-carb...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	86	n/a	n/a	n/a	n/a	n/a	n/a
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MAP kinase-interacting serine/threonine-protein kinase 1 (Human)	BDBM375544 (US9908886, Example 96 | 4-(6-(4-(morpholine-4-carb...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	64	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
MAP kinase-interacting serine/threonine-protein kinase 2 (Human)	BDBM375544 (US9908886, Example 96 | 4-(6-(4-(morpholine-4-carb...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	9.40	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
MAP kinase-interacting serine/threonine-protein kinase 1 (Human)	BDBM375544 (US9908886, Example 96 | 4-(6-(4-(morpholine-4-carb...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
MAP kinase-interacting serine/threonine-protein kinase 1 (Human)	BDBM375544 (US9908886, Example 96 | 4-(6-(4-(morpholine-4-carb...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
MAP kinase-interacting serine/threonine-protein kinase 1 (Human)	BDBM375544 (US9908886, Example 96 | 4-(6-(4-(morpholine-4-carb...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	64	n/a	n/a	n/a	n/a	n/a	n/a
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MAP kinase-interacting serine/threonine-protein kinase 1/2 (Human)	BDBM375544 (US9908886, Example 96 | 4-(6-(4-(morpholine-4-carb...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	321	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 3A4 (Human)	BDBM375544 (US9908886, Example 96 | 4-(6-(4-(morpholine-4-carb...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 2D6 (Human)	BDBM375544 (US9908886, Example 96 | 4-(6-(4-(morpholine-4-carb...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
MAP kinase-interacting serine/threonine-protein kinase 2 (Human)	BDBM375544 (US9908886, Example 96 | 4-(6-(4-(morpholine-4-carb...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	86	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
MAP kinase-interacting serine/threonine-protein kinase 1 (Human)	BDBM375544 (US9908886, Example 96 | 4-(6-(4-(morpholine-4-carb...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	64	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
MAP kinase-interacting serine/threonine-protein kinase 2 (Human)	BDBM375544 (US9908886, Example 96 | 4-(6-(4-(morpholine-4-carb...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair