BDBM37595 1-[3-(dimethylamino)propyl]-2-(3-methoxyphenyl)-3-(5-methylfuran-2-yl)carbonyl-4-oxidanyl-2H-pyrrol-5-one::1-[3-(dimethylamino)propyl]-3-hydroxy-5-(3-methoxyphenyl)-4-(5-methyl-2-furoyl)-3-pyrrolin-2-one::1-[3-(dimethylamino)propyl]-4-hydroxy-2-(3-methoxyphenyl)-3-(5-methylfuran-2-carbonyl)-2H-pyrrol-5-one::1-[3-(dimethylamino)propyl]-4-hydroxy-2-(3-methoxyphenyl)-3-[(5-methyl-2-furanyl)-oxomethyl]-2H-pyrrol-5-one::MLS000112915::SMR000108823::cid_2919053

SMILES COc1cccc(c1)C1C(C(=O)c2ccc(C)o2)C(=O)C(=O)N1CCCN(C)C

InChI Key InChIKey=SURLSKDZECACTH-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 37595   

TargetHuntingtin(Human)
Columbia University Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM37595(SMR000108823 | 1-[3-(dimethylamino)propyl]-2-(3-me...)
Affinity DataIC50: 8.00E+3nMAssay Description:The mutation underlying Huntington's disease is an expansion of a polyglutamine tract in the N-terminus of the protein huntingtin (htt). Under no...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2011
Entry Details
PCBioAssay