BDBM376008 6-[5-({[2-chloro-4- (trifluoromethyl)phenyl] carbonyl}amino)-1-phenyl-1H- pyrazol-3-yl]pyridine-3- carboxamide::US9914736, Compound 4

SMILES NC(=O)c1ccc(nc1)-c1cc(NC(=O)c2ccc(cc2Cl)C(F)(F)F)n(n1)-c1ccccc1

InChI Key InChIKey=HTLFDPDDWWWQMA-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 376008   

TargetHigh affinity nerve growth factor receptor(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM376008(US9914736, Compound 4 | 6-[5-({[2-chloro-4- (trifl...)
Affinity DataIC50: 48nMAssay Description: In this assay, U2OS cells express the human TrkA receptor as a fusion with the weakly complementing fragment of B-galactosidase, which DiscoverX cal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/30/2020
Entry Details
US Patent