BDBM376014 2-chloro-N-[3-(6-oxo-1,6- dihydropyridazin-3-yl)-1- phenyl-1H-pyrazol-5-yl]-4- (trifluoromethyl)benzamide::US9914736, Compound 10

SMILES FC(F)(F)c1ccc(C(=O)Nc2cc(nn2-c2ccccc2)-c2ccc(=O)[nH]n2)c(Cl)c1

InChI Key InChIKey=CPTJOCIMHXOLAQ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 376014   

TargetHigh affinity nerve growth factor receptor(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM376014(US9914736, Compound 10 | 2-chloro-N-[3-(6-oxo-1,6-...)
Affinity DataIC50: 290nMAssay Description: In this assay, U2OS cells express the human TrkA receptor as a fusion with the weakly complementing fragment of B-galactosidase, which DiscoverX cal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/30/2020
Entry Details
US Patent