BDBM376020 N-[3-(4-methyl-5-oxo-4,5- dihydro-1H-1,2,4-triazol-3- yl)-1-phenyl-1H-pyrazol-5-yl]- 3-(1-methyl-1H-pyrazol-3-yl)- 4-(trifluoromethyl)benzamide::US9914736, Compound 16

SMILES Cn1ccc(n1)-c1cc(ccc1C(F)(F)F)C(=O)Nc1cc(nn1-c1ccccc1)-c1n[nH]c(=O)n1C

InChI Key InChIKey=HFBQFCFGZKIYNB-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 376020   

TargetHigh affinity nerve growth factor receptor(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM376020(US9914736, Compound 16 | N-[3-(4-methyl-5-oxo-4,5-...)
Affinity DataIC50: 46nMAssay Description: In this assay, U2OS cells express the human TrkA receptor as a fusion with the weakly complementing fragment of B-galactosidase, which DiscoverX cal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/30/2020
Entry Details
US Patent