BDBM376039 N-[1-(4-fluorophenyl)-3- pyridin-4-yl-1H-pyrazol-5-yl]- 3-pyridin-3-yl-4- (trifluoromethyl)benzamide::US9914736, Compound 35

SMILES Fc1ccc(cc1)-n1nc(cc1NC(=O)c1ccc(c(c1)-c1cccnc1)C(F)(F)F)-c1ccncc1

InChI Key InChIKey=OMVZQDAJJCCUCL-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 376039   

TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM376039(N-[1-(4-fluorophenyl)-3- pyridin-4-yl-1H-pyrazol-5...)
Affinity DataIC50:  1.70E+3nMAssay Description: In this assay, U2OS cells express the human TrkA receptor as a fusion with the weakly complementing fragment of B-galactosidase, which DiscoverX cal...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent