BDBM376064 N-[1-(4-fluorophenyl)-3- pyrimidin-2-yl-1H-pyrazol-5- yl]-3-(1-methyl-1H-pyrazol-3- yl)-4- (trifluoromethyl)benzamide::US9914736, Compound 60

SMILES Cn1ccc(n1)-c1cc(ccc1C(F)(F)F)C(=O)Nc1cc(nn1-c1ccc(F)cc1)-c1ncccn1

InChI Key InChIKey=JAXUIDUVQJTDOY-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 376064   

TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM376064(N-[1-(4-fluorophenyl)-3- pyrimidin-2-yl-1H-pyrazol...)
Affinity DataIC50:  3nMAssay Description: In this assay, U2OS cells express the human TrkA receptor as a fusion with the weakly complementing fragment of B-galactosidase, which DiscoverX cal...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent