BDBM376383 N-(3-(cyclopropyl- methylcarbamoyl) benzyl)-6-methyl-6H- isochromeno[3,4-c]pyridine-8- carboxamide::US9914740, VIII-9

SMILES CC1Oc2cnccc2-c2ccc(cc12)C(=O)NCc1cccc(c1)C(=O)N(C)C1CC1

InChI Key InChIKey=YRRJBSUMKZSOQJ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 376383   

TargetRho-associated protein kinase 2(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM376383(N-(3-(cyclopropyl- methylcarbamoyl) benzyl)-6-meth...)
Affinity DataIC50:  2.55nMAssay Description:The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent