BDBM37650 3-(1-benzofuran-2-carbonyl)-2-(2,5-dimethoxyphenyl)-4-hydroxy-1-(5-methyl-1,2-oxazol-3-yl)-2H-pyrrol-5-one::3-(1-benzofuran-2-ylcarbonyl)-2-(2,5-dimethoxyphenyl)-1-(5-methyl-1,2-oxazol-3-yl)-4-oxidanyl-2H-pyrrol-5-one::3-[2-benzofuranyl(oxo)methyl]-2-(2,5-dimethoxyphenyl)-4-hydroxy-1-(5-methyl-3-isoxazolyl)-2H-pyrrol-5-one::4-(benzofuran-2-carbonyl)-5-(2,5-dimethoxyphenyl)-3-hydroxy-1-(5-methylisoxazol-3-yl)-3-pyrrolin-2-one::MLS000039507::SMR000058011::cid_661828

SMILES COc1ccc(OC)c(c1)C1C(C(=O)c2cc3ccccc3o2)C(=O)C(=O)N1c1cc(C)on1

InChI Key InChIKey=QZVYMQZBSVYVDW-UHFFFAOYSA-N

Data  2 KI  3 IC50  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 37650   

TargetfMet-Leu-Phe receptor(Homo sapiens (Human))
Nmmlsc

Curated by PubChem BioAssay
LigandPNGBDBM37650(3-(1-benzofuran-2-carbonyl)-2-(2,5-dimethoxyphenyl...)
Affinity DataKi:  2.39E+4nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH 1R03MH076381-01 Assay for Formylpeptide Receptor Family Ligands PI: Bruce S. Edwards, Ph...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetN-formyl peptide receptor 2(Homo sapiens (Human))
Nmmlsc

Curated by PubChem BioAssay
LigandPNGBDBM37650(3-(1-benzofuran-2-carbonyl)-2-(2,5-dimethoxyphenyl...)
Affinity DataKi: >4.03E+4nMAssay Description:University of New Mexico Assay Overview Assay Support: NIH 1R03MH076381-01 Assay for Formylpeptide Receptor Family Ligands PI: Bruce S. Edwards, Ph....More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetGenome polyprotein(Hepatitis C virus)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM37650(3-(1-benzofuran-2-carbonyl)-2-(2,5-dimethoxyphenyl...)
Affinity DataIC50:  5.29E+3nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Center Affiliation: The Scripps Research Institute (TS...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetSerine/threonine-protein phosphatase(Candida dubliniensis CD36)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM37650(3-(1-benzofuran-2-carbonyl)-2-(2,5-dimethoxyphenyl...)
Affinity DataEC50:  1.80E+5nMAssay Description:Keywords: Candida albicans, drug resistance, Fluconazole, calcineurin, stress response Assay Overview: Method for determining if compound acts as Ca...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetATP-dependent molecular chaperone HSP82(Candida albicans)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM37650(3-(1-benzofuran-2-carbonyl)-2-(2,5-dimethoxyphenyl...)
Affinity DataEC50:  2.16E+4nMAssay Description:Keywords: Candida albicans, drug resistance, Fluconazole, Hsp90, stress response Assay Overview: Method for determining if compound acts as Hsp90 inh...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetATP-dependent molecular chaperone HSP82(Candida albicans)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM37650(3-(1-benzofuran-2-carbonyl)-2-(2,5-dimethoxyphenyl...)
Affinity DataEC50: <120nMAssay Description:Broad Institute: Reversing Antifungal Drug Resistance Project ID: 2037 Keywords: Candida albicans, drug resistance, Fluconazole, Hsp90, Calcineurin, ...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetN-formyl peptide receptor 2(Homo sapiens (Human))
Nmmlsc

Curated by PubChem BioAssay
LigandPNGBDBM37650(3-(1-benzofuran-2-carbonyl)-2-(2,5-dimethoxyphenyl...)
Affinity DataIC50: >6.67E+4nMAssay Description:University of New Mexico Assay Overview Assay Support: NIH 1R03MH076381-01 Assay for Formylpeptide Receptor Family Ligands PI: Bruce S. Edwards, Ph....More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetfMet-Leu-Phe receptor(Homo sapiens (Human))
Nmmlsc

Curated by PubChem BioAssay
LigandPNGBDBM37650(3-(1-benzofuran-2-carbonyl)-2-(2,5-dimethoxyphenyl...)
Affinity DataIC50:  3.66E+4nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH 1R03MH076381-01 Assay for Formylpeptide Receptor Family Ligands PI: Bruce S. Edwards, Ph...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetATP-dependent molecular chaperone HSP82(Candida albicans)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM37650(3-(1-benzofuran-2-carbonyl)-2-(2,5-dimethoxyphenyl...)
Affinity DataEC50: >1.50E+5nMAssay Description:Keywords: Candida albicans, drug resistance, Fluconazole, Hsp90, Calcineurin, stress response Primary Collaborators: Susan Lindquist, Whitehead Insti...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay